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Differential Effects of Adrenergic Antagonists (Carvedilol vs. Metoprolol) on Parasympathetic and Sympathetic Activity: A Comparison of Measures 1 of 2

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BACKGROUND  Cardiovascular autonomic neuropathy (CAN) is recognized as a significant health risk. Specific and sensitive measures of CAN are needed for early identification and treatment to avoid complications, preferably in the preclinical state.  OBJECTIVES  In this first of two articles, the patient cohort is described and two measures of autonomic function are reviewed: the traditional […]

Differential Effects of Adrenergic Antagonists (Carvedilol vs. Metoprolol) on Parasympathetic and Sympathetic Activity: A Comparison of Measures 1 of 2 Read More »

Differential Effects of Adrenergic Antagonists (Carvedilol vs. Metoprolol) on Parasympathetic and Sympathetic Activity: A Comparison of Measures 2 of 2

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BACKGROUND  Cardiovascular autonomic neuropathy (CAN) is recognized as a significant health risk, correlating with risk of heart disease, silent myocardial ischemia or sudden cardiac death. Beta-blockers are often prescribed to minimize risk.  OBJECTIVES  In this second of two articles, the effects on parasympathetic and sympathetic activity of the alpha/beta-adrenergic blocker, Carvedilol, are compared with those

Differential Effects of Adrenergic Antagonists (Carvedilol vs. Metoprolol) on Parasympathetic and Sympathetic Activity: A Comparison of Measures 2 of 2 Read More »

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