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— Who We Serve · Research & Clinical Trials
ANS Research Software for Autonomic Studies
A research-grade platform on a one-year renewable license, backed by published studies and used at multiple research institutions.
See the technology live in a 60-minute
virtual session.
— Who We Serve ·
Research & Clinical Trials
ANS Research Software for Autonomic Studies
A research-grade platform on a one-year renewable license, backed by published studies and used at multiple research institutions.
See the technology live in a 60-minute virtual session.
— The Research Case
An Established Evidence Base, Not a Stripped-Down Build
Physio PS 4.0 is the same platform that underpins the clinical monitoring units, made available to approved researchers under a one-year renewable research license. It has been used at multiple research institutions and has contributed to published studies and books.
For work involving autonomic dysfunction, cardiac autonomic neuropathy, or parasympathetic and sympathetic function, the differentiator is measurement: both branches independently, simultaneously and quantitatively, which no other tool on the market provides. That includes exposure studies such as aerotoxicity, where the autonomic signature is the endpoint of interest.
Built on the same platform used by physicians and researchers worldwide, not a stripped-down academic version
A one-year renewable license gives research teams sustained access without long-term procurement barriers
Backed by published research, so you build on an established evidence base rather than starting from scratch
Measures both parasympathetic and sympathetic branches independently and simultaneously, a capability no other tool provides
— The Research Case
An Established Evidence Base, Not a Stripped-Down Build
Physio PS 4.0 is the same platform that underpins the clinical monitoring units, made available to approved researchers under a one-year renewable research license. It has been used at multiple research institutions and has contributed to published studies and books.
For work involving autonomic dysfunction, cardiac autonomic neuropathy, or parasympathetic and sympathetic function, the differentiator is measurement: both branches independently, simultaneously and quantitatively, which no other tool on the market provides. That includes exposure studies such as aerotoxicity, where the autonomic signature is the endpoint of interest.
Built on the same platform used by physicians and researchers worldwide, not a stripped-down academic version
A one-year renewable license gives research teams sustained access without long-term procurement barriers
Backed by published research, so you build on an established evidence base rather than starting from scratch
Measures both parasympathetic and sympathetic branches independently and simultaneously, a capability no other tool provides
— CONDITIONS
Research Areas the Platform Supports
Autonomic endpoints across the specialties represented in the full condition index.
Cardiac Autonomic Neuropathy
A measurable autonomic endpoint with established mortality significance.
Post-COVID / Long-COVID
Autonomic dysfunction from a variety of causes, including post-COVID presentations.
Aerotoxicity and Exposure Studies
Autonomic response as the endpoint in occupational and environmental exposure work.
PTSD and Trauma
Both branches involved, with quality-of-life symptoms as the measurable layer.
Autonomic Dysfunction
Both branches quantified independently, across an estimated 90 million affected people.
POTS
The sympathetic response to standing is quantified, differentiating orthostatic dysfunction from syncope.
Diabetic Autonomic Neuropathy
Sympathetic excess, then the continuing effects of sugar acidosis on the vagus nerve.
Pharmacological Response
Most drugs affect only one branch; monitoring quantifies individual response to therapy.
— In the Room
What the Visit Looks Like
Patient seated, leads placed
A heart rate monitor, ECG leads and a blood pressure cuff. Nothing invasive, no tilt table.
Both branches resolved separately
The software measures RFa and LFa, giving parasympathetic and sympathetic activity as two independent readings.
Report before the patient leaves
Qualitative, quantitative and graphical output, ready for your review and for the patient to take home.
— Access and Setup
One-Year Renewable Research License
Researchers apply for access via an online form on the Research Center page. Licenses are reviewed and granted to approved applicants, on a one-year renewable basis.
Ask about configuration and licensing during your demo.
— CONDITIONS
Research Areas the Platform Supports
Autonomic endpoints across the specialties represented in the full condition index.
Cardiac Autonomic Neuropathy
A measurable autonomic endpoint with established mortality significance.
Post-COVID / Long-COVID
Autonomic dysfunction from a variety of causes, including post-COVID presentations.
Aerotoxicity and Exposure Studies
Autonomic response as the endpoint in occupational and environmental exposure work.
PTSD and Trauma
Both branches involved, with quality-of-life symptoms as the measurable layer.
Autonomic Dysfunction
Both branches quantified independently, across an estimated 90 million affected people.
POTS
The sympathetic response to standing quantified, where tilt-table struggles to differentiate.
Diabetic Autonomic Neuropathy
Sympathetic excess, then the continuing effects of sugar acidosis on the vagus nerve.
Pharmacological Response
Most drugs affect only one branch; monitoring quantifies individual response to therapy.
— In the Room
What the Visit Looks Like
Patient seated, leads placed
A heart rate monitor, ECG leads and a blood pressure cuff. Nothing invasive, no tilt table.
Both branches resolved separately
The software measures RFa and LFa, giving parasympathetic and sympathetic activity as two independent readings.
Report before the patient leaves
Qualitative, quantitative and graphical output, ready for your review and for the patient to take home.
— ACCESS and Setup
One-Year Renewable Research License
Researchers apply for access via an online form on the Research Center page. Licenses are reviewed and granted to approved applicants, on a one-year renewable basis.
Ask about configuration and licensing during your demo.
✓ FDA 510(k) Cleared
✓ Patented Technology
✓ Backed by Published Research
Apply for a Research License
See the technology live in a 60-minute virtual session.
✓ FDA 510(k) Cleared ✓ Patented Technology ✓ Backed by Published Research ✓ In Business Since 2019
— Next Step
Start Where It Makes Sense for You
FDA 510(k) cleared autonomic nervous system monitoring for clinics, home care and research. Serving physicians, clinics and researchers across the United States and worldwide.
Site
Who We Serve
Journal
Contact
603-287-1817
80 Nashua Rd, Building C, Unit G1, Londonderry, NH 03053
© 2026 Physio PS, Inc. All rights reserved. FDA 510(k) cleared · Patented · Established 2019.
Hours available on request, ask during your demo.
Copyright 2026 Physio PS, Inc. All Rights Reserved.
The material and information provided by Physio PS is for general information purposes only. You should not rely upon this material or information for basis of making healthcare, treatment, or diagnosis decisions. While Physio PS strives to provide the most correct and up-to-date information and data, Physio PS makes no representations or warranties of any kind, expressed or implied, about the completeness, accuracy, reliability, suitability, or availability with respect to the information, products, services, or related graphics contained. Any reliance placed on such material is therefore strictly at your own risk. Reporting Information is supplied under license by NCRC LLC. * ‘RFa’ is known to be a measure of Parasympathetic activity and ‘LFa’ is known to be a measure of Sympathetic activity, based on reference: Colombo J, Arora RR, DePace NL, Vinik AI, Clinical Autonomic Dysfunction: Measurement, Indications, Therapies, and Outcomes. Springer Science + Business Media, New York, NY; 2014.
— FAQ
Questions Practices Ask Before They Start
Straight answers on time, cost, clearance and fit.
How long does an assessment take?
A complete autonomic assessment is non-invasive and takes 15 minutes. It is fully automated, and the qualitative, quantitative and graphical reports are delivered without manual interpretation.
Is the technology FDA cleared?
Yes. The platform is FDA 510(k) cleared to U.S. medical device standards, patented, and backed by published research.
How is testing paid for?
The Clinical Monitoring Unit is supported by fundable billing codes. For the other systems, ask about billing code applicability during your demo. Financing options, low monthly payments and veteran-owned discounts are available to qualifying practices.
Do we need extra staff, space or a tilt table?
No. Testing integrates with your existing treatment protocols with no workflow overhaul and no tilt table required. Training and certification are included, so your team is ready from day one.
How is this different from heart rate variability tools?
It is the only solution on the market that measures both parasympathetic and sympathetic branches independently, simultaneously and quantitatively, rather than reporting one blended figure.
Which system fits my practice?
The CMU is a desktop system for clinics, the RMU is tablet-based and battery-powered for home care and sports medicine, and the PAL is laptop-based for medical professionals who move between facilities. A free demo is the quickest way to find the right configuration.
How do I become a distributor?
Tell us about your territory and the clinics you work with through the distributor enquiry form, or call 603-287-1817, and the team will follow up to discuss distribution.
Apply for a Research License
See the technology live in a 60-minute virtual session.
✓ FDA 510(k) Cleared ✓ Patented Technology ✓ Backed by Published Research
— Next Step
Start Where It Makes Sense for You
FDA 510(k) cleared autonomic nervous system monitoring for clinics, home care and research. Serving physicians, clinics and researchers across the United States and worldwide.
Site
Who We Serve
Journal
Contact
603-287-1817
80 Nashua Rd, Building C, Unit G1, Londonderry, NH 03053
© 2026 Physio PS, Inc. All rights reserved.
FDA 510(k) cleared · Patented · Established 2019.
Hours available on request, ask during your demo.
Copyright 2026 Physio PS, Inc. All Rights Reserved.
The material and information provided by Physio PS is for general information purposes only. You should not rely upon this material or information for basis of making healthcare, treatment, or diagnosis decisions. While Physio PS strives to provide the most correct and up-to-date information and data, Physio PS makes no representations or warranties of any kind, expressed or implied, about the completeness, accuracy, reliability, suitability, or availability with respect to the information, products, services, or related graphics contained. Any reliance placed on such material is therefore strictly at your own risk. Reporting Information is supplied under license by NCRC LLC. * ‘RFa’ is known to be a measure of Parasympathetic activity and ‘LFa’ is known to be a measure of Sympathetic activity, based on reference: Colombo J, Arora RR, DePace NL, Vinik AI, Clinical Autonomic Dysfunction: Measurement, Indications, Therapies, and Outcomes. Springer Science + Business Media, New York, NY; 2014.